Mixing of two COVID-19 vaccines

Will different vaccine doses be more effective?

Mixing of two COVID-19 vaccines
Mixing-of-two-COVID-19-vaccines

Taking two doses of different vaccines can lead to the development of more antibodies than taking two doses of the same vaccine. The report of a recent study in Britain has been confirmed. In January, all adults in Germany were given the AstraZeneca vaccine to protect against COVID-19, following approval from the European Medicines Agency.

 However, there was an increased risk of blood clots in the brain, especially in some young women, after being vaccinated. For this reason, in April, Germany's Standing Committee on Immunization (Stico) recommended limiting the use of this vaccine to people over the age of 60. However, by then a large number of people had already taken their first dose of AstraZeneca. These people had to get the Biotech-Pfizer or Moderna vaccine as a second dose. Today in Germany people of any age can get the AstraZeneca vaccine.

The new study suggests that applying two different vaccines may prove to be more effective. Researchers at the University of Oxford found that patients who received the first dose of AstraZeneca and four weeks later the second dose of the Biotech-Pfizer vaccine developed more antibodies than those who received two doses of AstraZeneca. As part of the Com-CoV trial, the Oxford researchers administered two different vaccines to 830 volunteers over the age of 50. According to the results, the highest antibodies developed in people who took two doses of BioNTech. Next, there were those who took one dose of AstraZeneca and the other with BioNTech. Then there were the people who took two doses of AstraZeneca.